業績


原著論文

Ubiquitin-like 3 as a new protein-sorting factor for small extracellular vesicles.
Takanashi Y, Kahyo T, Kamamoto S, Zhang H, Chen B, Ping Y, Mizuno K, Kawase A, Koizumi K, Satou M, Funai K, Shiiya N, Setou M.
Cell Struct Funct. 2022;47(1):1-18. doi: 10.1247/csf.21078.
PMID: 35197392


The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2018 edition.
Shimoi T, Nagai SE, Yoshinami T, Takahashi M, Arioka H, Ishihara M, Kikawa Y, Koizumi K, Kondo N, Sagara Y, Takada M, Takano T, Tsurutani J, Naito Y, Nakamura R, Hattori M, Hara F, Hayashi N, Mizuno T, Miyashita M, Yamashita N, Yamanaka T, Saji S, Iwata H, Toyama T.
Breast Cancer. 2021 Jul;28(4):985-986. doi: 10.1007/s12282-021-01252-x.
PMID: 33886078


Preoperative concurrent endocrine therapy with chemotherapy in luminal B-like breast cancer.
Matsunuma R, Watanabe T, Hozumi Y, Koizumi K, Ito Y, Maruyama S, Ogura H, Goto K, Mori H, Sawai N, Shiiya N.
Breast Cancer. 2020 Sep;27(5):819-827. doi: 10.1007/s12282-020-01077-0. Epub 2020 Mar 6.
PMID: 32144735 Clinical Trial.


Trastuzumab, pertuzumab, and eribulin mesylate versus trastuzumab, pertuzumab, and a taxane as a first-line or second-line treatment for HER2-positive, locally advanced or metastatic breast cancer: study protocol for a randomized controlled, non-inferiority, phase III trial in Japan (JBCRG-M06/EMERALD).
Yamashita T, Masuda N, Saji S, Araki K, Ito Y, Takano T, Takahashi M, Tsurutani J, Koizumi K, Kitada M, Kojima Y, Sagara Y, Tada H, Iwasa T, Kadoya T, Iwatani T, Hasegawa H, Morita S, Ohno S.
Trials. 2020 Jun 8;21(1):503. doi: 10.1186/s13063-020-04408-w.
PMID: 32513251


Efficacy of denosumab for restoring normal bone mineral density in women receiving adjuvant aromatase inhibitors for early breast cancer.
Sakaguchi K, Ono H, Nakatsukasa K, Ishikawa T, Hasegawa Y, Takahashi M, Niikura N, Koizumi K, Sakurai T, Shigematsu H, Takahashi S, Taira S, Suzuki M, Narui K, Miura D, Yamada K, Yoshimura M, Shioya H, Konishi E, Isao Y, Imai K, Fujikawa K, Taguchi T; Collaborative Study Group of Scientific Research of the Japanese Breast Cancer Society.
Medicine (Baltimore). 2019 Aug;98(32):e16770. doi: 10.1097/MD.0000000000016770.
PMID: 31393399


The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2018 edition.
Shimoi T, Nagai SE, Yoshinami T, Takahashi M, Arioka H, Ishihara M, Kikawa Y, Koizumi K, Kondo N, Sagara Y, Takada M, Takano T, Tsurutani J, Naito Y, Nakamura R, Hattori M, Hara F, Hayashi N, Mizuno T, Miyashita M, Yamashita N, Yamanaka T, Saji S, Iwata H, Toyama T.
Breast Cancer. 2020 May;27(3):322-331. doi: 10.1007/s12282-020-01085-0. Epub 2020Apr 2.
PMID: 32240526


Dose-dense adjuvant chemotherapy: a systematic review and meta-analysis of the Japanese Breast Cancer Society Clinical Practice Guideline, 2018 edition.
Yoshinami T, Koizumi K, Nagai SE, Toyama T, Iwata H.
Breast Cancer. 2020 May;27(3):334-339. doi: 10.1007/s12282-019-01039-1. Epub 2020 Jan 8.
PMID: 31916188


Effect of denosumab on low bone mineral density in postmenopausal Japanese women receiving adjuvant aromatase inhibitors for non-metastatic breast cancer: 24-month results.
Nakatsukasa K, Koyama H, Ouchi Y, Ono H, Sakaguchi K, Matsuda T, Kato M, Ishikawa T, Yamada K, Yoshimura M, Koizumi K, Sakurai T, Shigematsu H, Takahashi S, Taira S, Suzuki M, Narui K, Niikura N, Hasegawa Y, Miura D, Konishi E, Taguchi T; Collaborative Study Group of Scientific Research of the Japanese Breast Cancer Society.
Breast Cancer. 2019 Jan;26(1):106-112. doi: 10.1007/s12282-018-0896-y. Epub 2018 Jul 27.
PMID: 30054855


Effect of Source-Detector Distance on the Measurement of Hemoglobin Using Near-Infrared Spectroscopy in Breast Cancer.
Hayashi M, Yoshizawa N, Ueda Y, Mimura T, Ohmae E, Yoshimoto K, Wada H, Nasu H, Ogura H, Sakahara H.
Technol Cancer Res Treat. 2019 Jan 1;18:1533033819830411. doi: 10.1177/1533033819830411.
PMID: 30764728


Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy.
Ohmae E, Yoshizawa N, Yoshimoto K, Hayashi M, Wada H, Mimura T, Suzuki H, Homma S, Suzuki N, Ogura H, Nasu H, Sakahara H, Yamashita Y, Ueda Y.
Biomed Opt Express. 2018 Oct 29;9(11):5792-5808. doi: 10.1364/BOE.9.005792. eCollection 2018 Nov 1.
PMID: 30460162


A phase II, multicenter, single-arm trial of eribulin as first- or second-line chemotherapy for HER2-negative advanced or metastatic breast cancer: evaluation of efficacy, safety, and patient-reported outcomes.
Kimura K, Iwamoto M, Tanaka S, Yamamoto D, Yoshidome K, Ogura H, Terasawa R, Matsunami N, Takahashi Y, Nitta T, Morimoto T, Fujioka H, Kawaguchi K, Uchiyama K.
Cancer Chemother Pharmacol. 2018 May;81(5):923-933. doi: 10.1007/s00280-018-3567-y. Epub 2018 Mar 28.
PMID: 29594360


Factors affecting measurement of optic parameters by time-resolved near-infrared spectroscopy in breast cancer.
Yoshizawa N, Ueda Y, Mimura T, Ohmae E, Yoshimoto K, Wada H, Ogura H, Sakahara H.
J Biomed Opt. 2018 Feb;23(2):1-6. doi: 10.1117/1.JBO.23.2.026010.
PMID: 29488362


Recurrent triple-negative breast cancer (TNBC) tissues contain a higher amount of phosphatidylcholine (32:1) than non-recurrent TNBC tissues.
Hosokawa Y, Masaki N, Takei S, Horikawa M, Matsushita S, Sugiyama E, Ogura H, Shiiya N, Setou M.
PLoS One. 2017 Aug 23;12(8):e0183724. doi: 10.1371/journal.pone.0183724. eCollection 2017.
PMID: 28832678


Effect of the chest wall on the measurement of hemoglobin concentrations by near-infrared time-resolved spectroscopy in normal breast and cancer.
Yoshizawa N, Ueda Y, Nasu H, Ogura H, Ohmae E, Yoshimoto K, Takehara Y, Yamashita Y, Sakahara H.
Breast Cancer. 2016 Nov;23(6):844-850. doi: 10.1007/s12282-015-0650-7. Epub 2015 Oct 16.
PMID: 26474784


Near-Infrared Diffuse Optical Imaging for Early Prediction of Breast Cancer Response to Neoadjuvant Chemotherapy: A Comparative Study Using 18F-FDG PET/CT.
Ueda S, Yoshizawa N, Shigekawa T, Takeuchi H, Ogura H, Osaki A, Saeki T, Ueda Y, Yamane T, Kuji I, Sakahara H.
J Nucl Med. 2016 Aug;57(8):1189-95. doi: 10.2967/jnumed.115.167320. Epub 2016 Mar 3.
PMID: 26940765


Single-cell time-of-flight secondary ion mass spectrometry reveals that human breast cancer stem cells have significantly lower content of palmitoleic acid compared to their counterpart non-stem cancer cells.
Waki M, Ide Y, Ishizaki I, Nagata Y, Masaki N, Sugiyama E, Kurabe N, Nicolaescu D, Yamazaki F, Hayasaka T, Ikegami K, Kondo T, Shibata K, Hiraide T, Taki Y, Ogura H, Shiiya N, Sanada N, Setou M.
Biochimie. 2014 Dec;107 Pt A:73-7. doi: 10.1016/j.biochi.2014.10.003. Epub 2014 Oct 13.
PMID: 25312848


Human breast cancer tissues contain abundant phosphatidylcholine(36∶1) with high stearoyl-CoA desaturase-1 expression.
Ide Y, Waki M, Hayasaka T, Nishio T, Morita Y, Tanaka H, Sasaki T, Koizumi K, Matsunuma R, Hosokawa Y, Ogura H, Shiiya N, Setou M.
PLoS One. 2013 Apr 16;8(4):e61204. doi: 10.1371/journal.pone.0061204. Print 2013.
PMID: 23613812


Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH).
Kiyose S, Igarashi H, Nagura K, Kamo T, Kawane K, Mori H, Ozawa T, Maeda M, Konno K, Hoshino H, Konno H, Ogura H, Shinmura K, Hattori N, Sugimura H.
Pathol Int. 2012 Nov;62(11):728-34. doi: 10.1111/j.1440-1827.2012.02862.x.
PMID: 23121603


Time-resolved optical mammography and its preliminary clinical results.
Ueda Y, Yoshimoto K, Ohmae E, Suzuki T, Yamanaka T, Yamashita D, Ogura H, Teruya C, Nasu H, Ima E, Sakahara H, Oda M, Yamashita Y.
Technol Cancer Res Treat. 2011 Oct;10(5):393-401. doi: 10.7785/tcrt.2012.500217.
PMID: 21895025


症例報告

A difficult-to-diagnose fibromatosis-like metaplastic carcinoma of the breast: a case report.
Takatsuka D, Ogura H, Asano Y, Nakamura A, Koizumi K, Shiiya N, Baba S.
Surg Case Rep. 2021 Jan 12;7(1):16. doi: 10.1186/s40792-021-01110-0.
PMID: 33433770


Two cases of diabetic mastopathy: MR imaging and pathological correlation.
Nasu H, Ikeda A, Ogura H, Teruya C, Koizumi K, Kinoshita M, Tsuchida T, Baba S, Miura K, Takehara Y, Sakahara H.
Breast Cancer. 2015 Sep;22(5):552-6. doi: 10.1007/s12282-012-0407-5. Epub 2012 Sep 14.
PMID: 22976289


A case of Miller Fisher syndrome during preoperative chemotherapy for breast cancer.
Taki Y, Ide Y, Tajima S, Hosokawa Y, Matsunuma R, Terada T, Waki M, Ogura H, Shiiya N.
Int J Clin Exp Med. 2015 Sep 15;8(9):16914-7. eCollection 2015.
PMID: 26629243


Breast cancer metastatic to the kidney with renal vein involvement.
Nasu H, Miura K, Baba M, Nagata M, Yoshida M, Ogura H, Takehara Y, Sakahara H.
Jpn J Radiol. 2015 Feb;33(2):107-11. doi: 10.1007/s11604-014-0386-x. Epub 2014 Dec 28.
PMID: 25544028


Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy: A Case Study.
Miura K, Teruya C, Hatsuko N, Ogura H.
Case Rep Med. 2012;2012:569040. doi: 10.1155/2012/569040. Epub 2012 Apr 22.
PMID: 22577391


Double neuroendocrine ductal carcinomas in situ coexisting with a background of diffuse idiopathic neuroendocrine cell hyperplasia of breast: a case report and hypothesis of neuroendocrine tumor development.
Miura K, Nasu H, Ogura H.
Pathol Int. 2012 May;62(5):331-4. doi: 10.1111/j.1440-1827.2012.02786.x. Epub 2012 Feb 14.
PMID: 22524661


Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin.
Kawasaki H, Ogura H, Arai Y, Baba S, Kosugi I, Tsutsui Y, Iwashita T.
Pathol Int. 2010 Mar;60(3):228-34. doi: 10.1111/j.1440-1827.2009.02502.x.
PMID: 20403050


著書

小泉圭:乳癌診療ガイドライン1治療編2022年版 日本乳癌学会編 金原出版 2022


小泉圭:乳癌患者の妊娠・出産と生殖医療に関する診療ガイドライン 2021年版 日本がん・生殖医療学会編 金原出版


小泉圭:乳癌診療ガイドライン2018年版〔追補2019〕 日本乳癌学会編 金原出版 2019


小泉圭:乳癌診療ガイドライン1治療編2018年版 日本乳癌学会編 金原出版 2018


小泉圭: Expert choice 乳がんレジメン,先端医学社 2015


小泉圭:オンコロジークリニカルガイド 乳癌薬物療法,南山堂 2013


総説

小泉圭
乳がん患者の妊娠・出産ト生殖医療に関する診療ガイドライン改訂のポイント(乳癌関連)
日本がん・生殖医療学会誌 voi.5, No. 1, 16-22, 2022


研究業績